Ch 10 Cell Growth and Division Study Guide

Keep in mind that we are skipping 10.1 as it was covered on the first test ;)

Things you should know:

-What is a chromosome? What is it made of? Where are they found? Why are they important?

-What are the similarities between DNA, chromatin and chromosomes?

-What is/are the Centromere and sister chromatids?

BTW don’t confuse chromatin, chromatids and chromosomes. They are all related, but different things!

-What are the steps of the cell cycle and what happens in each step?
-What is the G1 checkpoint and why is it so important?

-What is different about the cell cycle of a cancer cell from a normal cell (especially with regard to that G1 checkpoint…)?

-What is mitosis? Distinguish mitosis and cytokinesis. What happens overall in each?

-What are the steps of mitosis and name the important things that happen at each step (tip: more happens in the first and last stages than in the middle ones).

-What are the mitotic spindle and the centrioles? What roles do they play?

-How is cell division different in plants and animals?

-Why do we need mitosis? (What purpose does it serve?)

-Give some examples of what determines if a cell can divide.

-What effect does crowding usually have on cell division? Why?

-What things in the environment can cause cancer? How does the environment cause cancer?

-What is p53? Why is it important?

-What is a stem cell? Why do we need them? Be able to distinguish different categories (toti-, pluri-, and multipotent) of stem cells? When does each type first show up during our development?

-What is a zygote, morula, blastula and gastrula? How do these terms relate to the previous question?

-Why is the term “adult” stem cells misleading?

-Be familiar with the stuff from the “Stem Cell Guy” activity.

-What is “differentiation”? What happens during the process?

-How are stem cells obtained for research? Why is this controversial? What is IVF and how does it relate to stem cells?

-Be able to give some examples of what types of diseases/injuries might be treated with stem cells.

-How might stem cells cause cancer?

-What are iPS cells? How do these affect the stem cell debate?
-Be able to identify/define/describe the terms from the play doh lab.